Zheng LIU, Ph. D.

Professor, Yangtze River Scholarship Professor of biochemical engineering

Department of Chemical Engineering,

Tsinghua University,   Beijing 100084, China 

Tel: +86-10-62779876

Fax: +86-10-62770304

Email: liuzheng@tsinghua.edu.cn

    Editor board, Chinese Journal of Chemical Engineering,

    International Advisory board, Canadian Journal of Chemical Engineering


Education and Scientific Career

Bachelor of Chemical Engineering, 1987

Dept. of Chemical Engineering, Tsinghua University.

Master of Chemical Engineering, 1989

Doctor of Chemical Engineering, 1993

UNESCO Fellow, 1993-1994

Dept. of Biochemical Engineering, Tokyo Institute of Technology

Lecturer (1993-1996)


Department of Chemical Engineering, Tsinghua University.


Associate Professor (1996-1998) 

Professor (1998 -)

 Research Interests:       


     Prof. Zheng Liu obtained his bachelor's, master's and doctoral degrees in chemical engineering from Tsinghua University in 1987, 1989 and 1993, respectively. He worked as a UNESCO Research Fellow at Tokyo Institute of Technology, Japan, during 1993 to 1994 and served as a Professor at department of chemical engineering, Tsinghua University since 1998.

     His recent research focuses on chemical and biomolecular engineering with special interests in protein conformational transition, nanostructured enzyme catalysts, and soil bioremediation techniques, and has resulted in 190 peer-reviewed journal papers. He has supervised over 40 graduate students, one of which received the National Best PhD Dissertation Award in 2008. Prof. Liu was awarded as Chang Jiang Scholars Professor of biochemical engineering, Ministry of Education, in 2012.


 Selected Publications

  1. Yifei Zhang, You Yong, Jun Ge and Zheng Liu*, Lectin agglutinated multienzyme catalyst with enhanced substrate affinity and activity, ACS Catal. 2016, 6, 3789-3795
  2. Xian Kong, Diannan Lu,* Jianzhong Wu* and Zheng Liu*, Spreading of a Unilamellar Liposome on Charged Substrates: A Coarse-Grained Molecular Simulation, Langmuir,2016, 32, 3785−3793.
  3. Xiaoling Wu, Jun Ge,* Jingying Zhu, Yifei Zhang, You Yong and Zheng Liu*,A general method for synthesizing enzyme–polymer conjugates in reverse emulsions using Pluronic as a reactive surfactant,Chem. Commun., 2015, 51, 9674-9677.
  4. Fengjiao Lyu, Yifei Zhang, Richard N. Zare, Jun Ge* and Zheng Liu*, One-Pot Synthesis of Protein-Embedded Metal−Organic Frameworks with Enhanced Biological Activities, Nano Letters, 2014, 14: 5761-5765.
  5. Yifei Zhang, Fengjiao Lyu, Jun Ge* and Zheng Liu*, Ink-jet printing an optimal multi-enzyme system, Chem, Commun, 2014, 50: 12919-12922.
  6. Zhixian Li, Yifei Zhang, Yechao Su, Pingkai Ouyang, Jun Ge* and Zheng Liu*, Spatial co-localization of multi-enzymes by inorganic nanocrystal–protein complexes, Chem Commun, 2014, 50: 12465-12468.
  7. Xian Kong, Zhixian Li, Diannan Lu,* Zheng Liu* and Jianzhong Wu*, Multiscale simulation of surfactant–aquaporin complex formation and water permeability, RSC Advances, 2014, 4, 37592–37599.
  8. Yifei Zhang, Qile Chen, Jun Ge* and Zheng Liu*, Controlled display of enzyme activity with a stretchable hydrogel, Chem Commun, 2013, 49:9815-7
  9. Jingying Zhu, YifeiZhang, Diannan Lu, RN Zare, Jun Ge* and Zheng Liu*, Temperature-responsive enzyme-polymer nanoconjugates with enhanced catalytic activities in organic media, Chem Commun, 2013, 49, 6090-6092.
  10. Rui Wang, Yifei Zhang, JinhaiHuang, Diannan Lu, Jun Ge*, Zheng Liu*, Substrate imprinted lipase nanogel for one-step synthesis of chloramphenicol palmitate, Green Chemistry, 2013, 15:1155-1158.
  11. Mengmeng Lin, Diannan Lu, Jingying Zhu, Cheng Yang, Yifei Zhang, and Zheng Liu*, Magnetic enzyme nanogels (MENGs): a universal synthetic route for biocatalysts. Chem Commun, 2012, 48: 3315–3317.
  12. Cheng Yang, Diannan Lu, and Zheng Liu*, How PEGylation Enhances the Stability and Potency of Insulin: A Molecular Dynamics Simulation, Biochemistry, 2011, 50:2585–2593.
  13. Binbin Zhu, Diannan Lu, Jun Ge, Zheng Liu*, Uniform polymer–protein conjugate by aqueous AGET ATRP using protein as a macroinitiator, Acta Biomaterialia, 2011,7:2131–2138.
  14. Zuojun Wu, Hongjun Dong, Liangdong Zou, Diannan Lu and Liu Zheng*, Enriched microbial community in bioaugmentation of petroleum-contaminated soil in the presence of wheat straw. Applied Biochemistry and Biotechnology, 2011, 164:1071-1082.
  15. Hua XF, Liu Zheng* et al., Degradation of hexadecane by Enterobacter cloacae strain TU that secretes an exopolysaccharide as a bioemulsifier, Chemosphere, 2010, 80:951-956.
  16. Jun Ge, Diannan Lu, Jun Wang, and Zheng Liu*, Lipase Nanogel Catalyzed transesterification in Anhydrous Dimethyl Sulfoxide, Biomacromolecules, 2009, 10:1612–1618.
  17. Diannan Lu and Zheng Liu*, Oscillatory Molecular Driving Force for Protein Folding at High concentration: A Molecular Simulation, J. Phys. Chem. B, 2008, 112:2686-2693.
  18. Diannan Lu, and Zheng Liu*, Dynamic Redox Environment-Intensified Disulfide Bond Shuffling for Protein Refolding in Vitro: Molecular Simulation and Experimental Validation, J. Phys. Chem. B , 2008, 112:15127-15133.
  19. Jun Ge, Diannan Lu, Jun Wang, Ming Yan, Yunfeng Lu, and Zheng Liu*, Molecular Fundamentals of Enzyme Nanogels, J. Phys. Chem. B, 2008, 112:14319-14324.
  20. Diannan Lu, Jianzhong Wu and Zheng Liu*, Dynamic Control of Protein Folding Pathway with a Polymer of Tunable Hydrophobicity, J. Phys. Chem. B, 2007,111, 12303-12309.
  21. Ming Yan, Zhixia Liu, Diannan Lu, and Zheng Liu*, Fabrication of single carbonic anhydrase nanogel against denaturation and aggregation at high temperature, Biomacromolecules, 2007, 8, 560-565.
  22. Ming Yan, Jun Ge, Zheng Liu*, Pingkai Ouyang, Encapsulation of Single Enzyme in Nanogel with Enhanced Biocatalytic Activity and Stability, J. Am. Chem. Soc., 2006, 128: 11008-11009.